• Wasps No8 will be out for up to four weeks with knee problem
• Alex Lozowski may start but Jonathan Joseph and Anthony Watson released
Sam Simmonds is poised for a first England start after Nathan Hughes was ruled out of England’s final autumn Test against Samoa on Saturday. Eddie Jones has also omitted the British & Irish Lions Anthony Watson and Jonathan Joseph in a number of changes made to his squad.
Hughes misses out with a bruised knee while Charlie Ewels and Nick Isiekwe will be part of the match-day squad and Alex Lozowski is expected to feature, having been retained in the 25-man squad. Simmonds, 23, has made brief cameo appearances off the bench in both autumn Tests so far but with Hughes out for up to a month and Sam Underhill due to be rested, he is set to line up against Samoa.